CO070. DOES ADENOSINE DEAMINASE (ADA)-CD26/DPPIV INTERACTION REGULATE ADIPOGENESIS?
نویسندگان
چکیده
منابع مشابه
Evaluation of Adenosine Deaminase (Ada) in Tuberculous Pleurisy
Tuberculosis is a global health problem whose morbidity and mortality is increasing, as one-third of the world population is estimated to be infected with Mycobacterium tuberculosis and eight million new active cases occur annually commonest being pulmonary tuberculosis and is often associated with effusion. Delay in diagnosis and treatment results in poor prognosis. Adenosine deaminase estimat...
متن کاملAdenosine deaminase (ADA) isoenzymes ADA1 and ADA2 in biological fluids.
We read with great interest the editorial by GAKIS [1] about the extreme importance of the adenosine deaminase (ADA) isoenzymes ADA1 and ADA2 on the homeostasis of 2' deoxyadenosine and adenosine, especially when monocytes and macrophages are infected by intracellular microorganisms. Serum ADA activity is increased in various conditions such as liver disease, tuberculosis, typhoid, infective mo...
متن کاملPurine Nucleoside Phosphorylase ( PNP ) and Adenosine Deaminase ( ADA ) Activities
New techniques have been devised for the cytochemical demonstration of purine nucleoside phosphorylase (PNP) and adenosine deaminase (ADA) activities in unfixed human lymphocytes. A suspension of living lymphocytes is mixed with agarose sol containing the reagents for the detection of PNP or ADA activity on a glass slide. The mixture solidifies. is incubated, and then dried for lightmicroscopic...
متن کاملPleural effusion adenosine deaminase (ADA) level and occult tuberculous pleurisy.
BACKGROUND We investigated the incidence of tuberculous pleurisy among patients with adenosine deaminase (ADA) levels of 50 IU/L or less in a pleural effusion, and without a previous diagnosis of carcinomatous pleurisy or Mycobacterium tuberculosis. SUBJECTS AND METHODS Subjects were selected from patients who had undergone pleural biopsy by thoracoscopy at National Hospital Organization Toky...
متن کاملCytokines regulate membrane adenosine deaminase on human activated lymphocytes.
CD26 is a lymphocyte marker that can anchor adenosine deaminase (ADA) on the T cell surface. We found that ADA is regulated by cytokines on the cell surface during T cell activation. By means of flow cytometry, immunofluorescence, and immunoblotting techniques, we found that interleukin (IL)-2 and IL-12 up-regulate ecto-ADA and CD26 expression. In clear contrast, IL-4 led to down-regulation of ...
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ژورنال
عنوان ژورنال: Revista Portuguesa de Endocrinologia, Diabetes e Metabolismo
سال: 2012
ISSN: 1646-3439
DOI: 10.1016/s1646-3439(12)70079-2